UN warns risk of hepatitis E in S. Sudan grows

GENEVA (AP) — The United Nations says an outbreak of hepatitis E has killed 111 refugees in camps in South Sudan since July, and has become endemic in the region.

U.N. refugee agency spokesman Adrian Edwards says the influx of people to the camps from neighboring Sudan is believed to be one of the factors in the rapid spread of the contagious, life-threatening inflammatory viral disease of the liver.

Edwards said Friday that the camps have been hit by 6,017 cases of hepatitis E, which is spread through contaminated food and water.

He says the largest number of cases and suspected cases is in the Yusuf Batil camp in Upper Nile state, which houses 37,229 refugees fleeing fighting between rebels and the Sudanese government.

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Hollywood directs its star power toward a campaign closer to home

A stylish crowd waited beneath a flashing marquee outside the Fonda Theatre. "Appearing tonight!" the sign read. "Eric Garcetti 4 Mayor."

In a city where political campaigns are typically waged at neighborhood meetings, not Hollywood concert halls, last week's star-studded fundraiser for Garcetti highlighted the entertainment industry's outsized role in this year's mayoral race. Talk show host Jimmy Kimmel started the show with a stand-up routine and musician Moby got the crowd of several hundred dancing. Actress Amy Smart urged everyone to tweet about the campaign, and actor Will Ferrell beamed in via video to pledge that if Garcetti is elected, every resident in the city will receive free waffles.

Hollywood is taking to City Hall politics like never before, veterans say, with power players such as Steven Spielberg leading a major fundraising effort and celebrities such as Salma Hayek weighing in via YouTube. A Times analysis of city Ethics Commission records found that actors, producers, directors and others in the industry have donated more than $746,000 directly to candidates, with some $462,000 going to Garcetti and $226,000 to City Controller Wendy Greuel.

Several of Greuel's big-name celebrity supporters, including Tobey Maguire, Kate Hudson and Zooey Deschanel, recently hosted a fundraiser for her at an exclusive club on the Sunset Strip. She is getting extra help from Spielberg and his former partners at DreamWorks, Jeffrey Katzenberg and David Geffen, who have given at least $150,000 and are raising more for an independent group funding a TV ad blitz on her behalf.

The burst of support is coming from an industry often maligned for paying little attention to local politics.

While Mayor Antonio Villaraigosa is often photographed at red carpet events and former Mayor Tom Bradley was famously close to actor Gregory Peck, serious Hollywood money and star power has tended to remain tantalizingly out of reach for local politicians. "It's no secret that the entertainment industry has never really focused on the city that houses it," said Steve Soboroff, who ran for mayor and lost in 2001.

Political consultant Garry South, who has worked on mayoral and gubernatorial campaigns, recalled having to pay celebrities to appear at fundraisers in the past. Hollywood has long embraced candidates in presidential and congressional elections, South said, in part because they have more influence over causes favored by celebrities.

"The mayor of L.A. is not going to get us out of Afghanistan. The mayor of L.A. is not going to determine whether or not gay marriage is legal," South said. "The local issues are just not as sexy."

But this year, if you're a part of the Hollywood establishment, chances are you've gotten invitations to fundraisers for Greuel, Garcetti or both.

The difference this time is that both candidates have worked to cultivate deep Hollywood connections, observers say. Garcetti has represented Hollywood for 12 years, overseeing a development boom and presiding over ceremonies to add stars — Kimmel recently got one — on the Hollywood Walk of Fame. Greuel is a former executive at DreamWorks, where she worked with the moguls who founded the studio. She has also served for 10 years on the board of the California Film Commission.

City Councilwoman Jan Perry and entertainment attorney Kevin James have reaped far less financial support from the industry, records show, although each claims a share of celebrity endorsements. Dick Van Dyke sponsored a fundraiser for Perry and Oscar winner Dustin Lance Black has given to James.

Agent Feroz Taj, who attended Garcetti's Moby concert, said a flurry of activity around the race, involving friends and colleagues, piqued his interest. He said he's never been involved in a political campaign, but now when he receives invites to Greuel events, he says he is supporting Garcetti.

Industry insiders have been buzzing about a letter they say is being circulated by an advisor to Spielberg and Katzenberg, urging people to give $15,000 to an independent group supporting Greuel. The DreamWorks founders have made a difference for Greuel in previous elections. In 2002, financial support from the studio executives and their allies helped her squeak out a victory in one of the closest City Council races in history.

This time around, billionaire media mogul Haim Saban is getting involved, providing his Beverly Hills estate for a Greuel fundraiser featuring U.S. Sen. Barbara Boxer (D-Calif.). Greuel has also received contributions from Tom Hanks and actresses Mariska Hargitay and Eva Longoria, neither of whom have given to a local political campaign before, according to records.

Garcetti, on the other hand, has picked up contributions from former Disney Chief Executive Michael Eisner, as well as newcomers to local politics Jake Gyllenhaal and Hayek, who once traveled with Garcetti on a global warming awareness mission to the South Pole. The actress released a video endorsing Garcetti and thanking him for helping her find her wallet in the snow.

Campaign consultant Sean Clegg linked the industry's burgeoning interest in mayoral politics to President Obama's election, which he said had "a catalyzing effect on Hollywood." Indeed, many Greuel and Garcetti supporters were Obama backers. Hayek hosted a fundraiser for Obama and Longoria served as a co-chair of his reelection campaign.

Clegg is a consultant for Working Californians, an independent campaign committee that hopes to raise and spend at least $2 million supporting Greuel, with donations from Spielberg and others in Hollywood, as well as the union representing Department of Water and Power employees.

Generally, Clegg argued, Hollywood money is different than the special-interest funding campaigns collect. "Money is coming out of the entertainment industry more on belief and less on the transactional considerations," he said.

But Raphael Sonenshein, director of the Pat Brown Institute of Public Affairs at Cal State L.A., said Hollywood's new interest in local elections may be tied to growing concerns about film production being lured elsewhere by tax incentives.

Garcetti and Greuel have both pledged to reverse job losses tied to runaway television and film production, with Garcetti touting a recent proposal to eliminate roughly $231,000 in annual city fees charged for pilot episodes of new TV shows. The number of pilots shot locally has dropped 30% in recent years, but city budget analysts say the tax break would have a minimal effect because city fees represent only a small portion of production costs.

On the council, both candidates voted to eliminate filming fees at most city facilities. Greuel tells audiences she has an insider's perspective on the industry's needs and says she will create an "entertainment cabinet" to help it thrive. "I have sat with studio heads," she said in a recent interview. "They want a city . . . that is a champion for film industry jobs in Los Angeles."

Greuel may have Garcetti beat on experience in the studio front office, but he is the only candidate with his own page on IMDb.com — a closely watched industry website that tracks individuals' film and television credits.

The councilman, a member of the Screen Actors Guild, has made several television appearances, including one for the cable police drama "The Closer." He played the mayor of Los Angeles.

kate.linthicum@latimes.com

Times staff writer Maloy Moore contributed to this report.

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IHT Rendezvous: How Much Do You Trust Journalists?

LONDON — Another poll came out this week showing that in the hierarchy of trust, journalists figure near the bottom of the heap.

Some of us take a perverse pride in being down there with the money-changers and the harlots (actually, the latter sometimes rate rather highly in these surveys.)

The comforting theory is that if everybody hates us, we must be doing something right.

The Ipsos MORI poll published on Friday found that among 1,018 British respondents, only one-in-five trusted journalists to tell the truth — on a par with bankers and below real estate agents.

Bizarrely, almost 70 percent trusted television news presenters — ahead of priests and other clergymen.

The only small consolation for the derided scribes was that they came out just ahead of politicians. Only 18 percent of respondents believed politicians could be relied on to tell the truth.

Now, the results may just reflect the current state of British journalism, and indeed of British politics.

In the latest development in a long-running phone-hacking scandal, Scotland Yard on Wednesday arrested six more journalists who previously worked for Rupert Murdoch’s now defunct News of the World.

The scandal already led to a months-long inquiry by Lord Justice Sir Brian Leveson, who concluded with an excoriating critique of the press as a whole for displaying “significant and reckless disregard for accuracy.”

Media-watchers believe, however, that in an era of rapid technological change, the trust issue goes wider than the morally dubious practices of some of the British red-top press.

As my colleague David Carr wrote at the height of the phone-hacking scandal last year: “Journalism’s ills don’t live exclusively on Fleet Street or stop at British shores.”

“Economic pressures have increased the urgency to make news and drive traffic, even as budgets have been cut and experienced news professionals tossed overboard,” David wrote.

He said part of the reason the public had lost confidence was that the product sometimes did not merit it. “If journalism is losing its way, that’s a story that needs to be told over and over,” he wrote.

An American student journal this week quoted Ron F. Smith, author of Ethics in Journalism, as saying the reputation of journalists was continually being questioned.

“Nearly every public opinion poll shows that people have lost respect for journalists and lost faith in the news media,” according to the introduction to his 2003 ethics manual.

Mariah Young, an aspiring journalist who writes for The Bullet, a student newspaper at Virginia’s University of Mary Washington, used the citation to ask whether journalists had lost a once cherished sense of ethics.

In an era of Twitter and the Internet, it was becoming harder for journalists to break news, papers to publish and people to trust the media, Ms. Young concluded.

There was similar soul-searching last month by John Lloyd, a veteran British commentator and Reuters columnist.

“The trend in a lot of the media is toward more scandal, more controversy and more opining,” he wrote, lamenting that news organizations wedded to objective reporting, investigation and rational analysis were now in a minority, “and a lot of them are finding it hard to make a living.”

He called for greater focus on long-term strategic issues such as global warming, dwindling resources and social change. “We should find some way of making this stuff part of a real global conversation — one that is vivid, comprehensible and more democratic,” he wrote.

In a comment to Mr. Lloyd, one anonymous news editor wrote, “Journalism has always attracted the self-righteous, opinionated and egotistical and with the new Facebook generation now in the workforce that bar is already at an all-time high.”

Has journalism really lost its way? Or does the public always get the press it deserves? And is the impact of citizen journalism a plus or a minus? Tell us what you think.

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Robin Roberts: My Dark Days, My Brave Fight

By Sharon Cotliar

02/16/2013 at 09:00 AM EST

Sitting in a white fluffy bathrobe in front of her bathroom mirror, Robin Roberts – still recuperating from a bone marrow transplant just five months earlier – seems at ease with her striking reflection. Just as she was after battling breast cancer in 2007, Roberts is once again bald, but this time she's skipping the wig.

"Whatever," the Good Morning America anchor says with a shrug. "I'm thankful I have a pretty-good-shaped head." And the 30 lbs. she's lost from her 5'10" frame during her month-long hospital stay? "It's been hard to put back on, a first in my life," she admits. "But I gained a pound last week in New Orleans. Woo-hoo!" And when Charlie Gibson, an old friend and former GMA cohort, drops by her Manhattan apartment and asks how she is, she replies as if nothing eventful has happened: "I'm good. How are you?" she says casually. "No, I wasn't being polite," Gibson replies. "I really want to know, 'How are you?' "

That's the question millions have been asking ever since the anchor left GMA last August to undergo a bone marrow transplant for a rare blood-and-bone-marrow disease called myelodysplastic syndrome, which can lead to a fast-growing form of leukemia.

"Every day I feel more like my old self. I didn't think I would," Roberts says, noting that she was so weak when she left the hospital in October, she could barely walk. While some shaky moments persist – "I've still got chemo brain and my vision is blurry" – Roberts is eager to return to her GMA anchor chair at last on Feb. 20, exactly five months after her transplant. "You feel so bad for so long, you just want to feel normal. And now I do."

She also has a new sense of perspective after fighting for her life for a second time. While Roberts, 52, projected an upbeat, brave persona in blog posts and tweets during her recovery, "it's important people know I'm not always like that," she says. "But I choose to be happy and not string together the bad days." Says her sister and bone marrow donor Sally-Ann: "We've been through a lot the last few months," including the death of their beloved mom, Lucimarian. "I marvel at Robin's strength."

It's a strength that was tested in April, when Roberts's doctor told her over the phone he suspected she had MDS. After looking it up on the Internet, "I was literally on the floor," she recalls. "I collapsed." But as GMA viewers know, she soon picked herself up and decided to go ahead with the grueling process of a bone marrow transplant; luckily her sister was a perfect match. Just as she was about to begin treatment, another life-altering event intervened: Roberts had to race home to Pass Christian, Miss., during Hurricane Isaac to say goodbye to her ailing mother, who died just hours after Roberts reached her on Aug. 30. The trip came at a pivotal moment for the terrified Roberts. "I don't care how old you are; when you're sick, you want your mom," she says, choking up. "And I wanted my mom."
 

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UN warns risk of hepatitis E in S. Sudan grows

GENEVA (AP) — The United Nations says an outbreak of hepatitis E has killed 111 refugees in camps in South Sudan since July, and has become endemic in the region.

U.N. refugee agency spokesman Adrian Edwards says the influx of people to the camps from neighboring Sudan is believed to be one of the factors in the rapid spread of the contagious, life-threatening inflammatory viral disease of the liver.

Edwards said Friday that the camps have been hit by 6,017 cases of hepatitis E, which is spread through contaminated food and water.

He says the largest number of cases and suspected cases is in the Yusuf Batil camp in Upper Nile state, which houses 37,229 refugees fleeing fighting between rebels and the Sudanese government.

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San Bernardino County sheriff details final shootout with Dorner

Fugitive Christopher Dorner spent his final hours barricaded inside a mountain cabin armed with a high-powered sniper rifle, smoke bombs and a cache of ammo, shooting to kill and ignoring commands to surrender until a single gunshot ended his life, authorities said Friday.

The evidence indicates that Dorner, a fired Los Angeles police officer suspected of killing four people and wounding three others, held a gun to his head and fired while the Big Bear area cabin he was holed up in caught fire, ignited by police tear gas.

San Bernardino County Sheriff John McMahon, during a news conference Friday, offered the most detailed account yet of the manhunt and final shootout, which left one of his deputies dead and another seriously wounded. McMahon steadfastly defended the tactics used by his agency, dismissing assertions that deputies may have botched the hunt for Dorner or deliberately set the cabin on fire.

"We stand confident in our actions on that fateful day," he said. "The bottom line is the deputy sheriffs of this department, and the law enforcement officers from the surrounding area, did an outstanding job. They ran into the line of fire. They were being shot at, and didn't turn around in retreat."

During Tuesday's shootout, a television news crew recorded law enforcement officials shouting to burn the cabin down. McMahon acknowledged the comments were made, but said they did not come from the department's tactical team or commanders on the scene.

"They had just been involved in probably one most of the most fierce firefights," he said of the people heard on the recording. "And sometimes, because we're humans, we say things that may or may not be appropriate. We will look into this and we will deal it appropriately."

The blaze started shortly after police fired "pyrotechnic" tear gas into the cabin; the canisters are known as "burners" because the intense heat they emit often causes a fire.

Sheriff's Capt. Gregg Herbert, who led the assault on the cabin, said the canisters were used only as a last resort after Dorner continued firing at deputies, ignored commands to surrender and did not respond when "cold," less intense tear gas was shot into the wood-framed dwelling.

Herbert said that a tractor was deployed to tear down walls of the cabin to expose Dorner's whereabouts inside, but that Dorner set off smoke bombs to hide himself. Storming the cabin was considered too dangerous because of the belief that Dorner "was lying in wait for us," he said.

"This was our only option," Herbert said of the pyrotechnic tear gas, adding that the potential for igniting a fire was taken into account.

After about a quarter of the cabin was engulfed in flames, Herbert said, "we heard a distinct single gunshot" come from inside. The shot sounded different from those Dorner had fired at deputies, indicating a different type of weapon was used, he said.

Dental records were used to confirm that the remains found in the cabin were indeed those of Dorner, 33.

The Riverside County coroner's office conducted an autopsy on Dorner, and determined that his death was caused by a single gunshot to the head. The coroner has not positively determined that Dorner shot himself, but the evidence "seems to indicate that the wound … was self inflicted," said Capt. Kevin Lacy of the San Bernardino County coroner's division.

From the cabin and vehicles Dorner used in the San Bernardino Mountains, investigators recovered a cache of weapons and ammunition. Among them: numerous assault weapons — including a bolt-action .308 caliber sniper's rifle — silencers, handguns, high-capacity magazines, smoke bombs, tear gas and a military-style Kevlar helmet.

McMahon said it was unclear how Dorner was able to carry all those weapons while on foot and on the run in Big Bear. But he said there's no evidence Dorner had an accomplice or received aid from anyone.

During Friday's news conference, McMahon also was pressed to address the anger and frustration of Big Bear residents who questioned how Dorner was able to hide out undetected for five days. In fact, Dorner was hiding in a vacation rental condominium less than 200 yards from law enforcement's command center during the manhunt.

The sheriff said the condo had been checked early in the search. The door was locked and no one answered when deputies knocked. Since there was no sign of forced entry on the door or windows, the deputies moved on.

McMahon said the decision was made not to kick open doors of unoccupied homes because they had no search warrants, and doing so would have included "hundreds" of homes — since many of the cabins and homes are unoccupied vacation homes.

Investigators later learned that the owners of the condo, Jim and Karen Reynolds, had left the unit unlocked to allow workers inside. When the Reynoldses entered the condo Tuesday morning, Dorner tied them up and stole their car. One of them was able to break free and call 911, leading to the deadly standoff at the mountain cabin in Angelus Oaks.

"I don't believe we made any mistakes," McMahon said.

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Meteorite Fragments Are Said to Rain Down on Siberia; 500 Injuries Reported

MOSCOW — Bright objects, apparently debris from a meteorite, streaked through the sky in western Siberia early on Friday, accompanied by a boom that damaged buildings across a vast area of territory. Around 500 people were reported to have been injured, most from breaking glass.

Emergency officials had reported no deaths by Friday afternoon but said that 14 people had been hospitalized.

Russian experts believe the blast was caused by a 10-ton meteor known as a bolide, which created a powerful shock wave when it reached the Earth’s atmosphere, the Russian Academy of Sciences said in a statement. Scientists believe the bolide exploded and evaporated at a height of around 20 to 30 miles above the Earth’s surface, but that small fragments may have reached the ground, the statement said.

The governor of the Chelyabinsk district reported that a search team had found an impact crater on the outskirts of a city about 50 miles west of Chelyabinsk. An official from the Interior Ministry told the Russian news agency Interfax that three large pieces of meteorite debris had been retrieved in the area and that 10,000 police officers are searching for more.

A small asteroid, known as 2012 DA14, is expected to pass close to Earth later on Friday, NASA reported on its Web site. Aleksandr Y. Dudorov, a physicist at Chelyabinsk State University, said it was possible that the meteorite may have been flying alongside the asteroid.

“What we witnessed today may have been the precursor of that asteroid,” said Mr. Dudorov in a telephone interview. Video clips from the city of Chelyabinsk showed an early morning sky illuminated by a brilliant flash, followed by the sound of breaking glass and multiple car alarms. Meteorites typically cause sonic booms as they enter the Earth’s atmosphere. On Friday, the force was powerful enough to shatter dishes and televisions in people’s homes.

“I saw a flash in the window, turned toward it and saw a burning cloud, which was surrounded by smoke and was going downward — it reminded me of what you see after an explosion,” said Maria Polyakova, 25, head of reception at the Park-City Hotel in Chelyabinsk, which is 950 miles east of Moscow. A video made outside a building in Chelyabinsk captured the astonished voices of witnesses who were uncertain what it was they had just seen.

“Maybe it was a rocket,” said one man, who rushed outside onto the street along with his co-workers when the object hit, far out of sight. A man named Artyom, who spoke to the Moscow FM radio station, said the explosion was enormous.

“I was sitting at work and the windows lit up and it was as if the whole city was illuminated, and I looked out and saw a huge streak in the sky and it was like that for two or three minutes and then I heard these noises, like claps,” he said. “And then all the dogs started barking.”

He said that there was a blast that caused balconies to shake and windows to shatter. He said he did not believe it was a meteorite. “We are waiting for a second piece, that is what people are talking about now,” the man said.

The object was visible from the city of Nizhniy Tagil, around 220 miles north of Chelyabinsk, where so many people called an emergency assistance number that it stopped working, the Novy Region news service reported.

The government response on Friday was huge. Seven airplanes were deployed to search for places where meteorites might have fallen and more than 20,000 people dispatched to comb the area on foot, according to the Ministry of Emergency Situations. There were also 28 sites designated to monitor radiation. No unusual readings had been detected, the ministry reported.

The area around Chelyabinsk is also home to “dozens of defense factories, including nuclear factories and those involved in production of thermonuclear weapons,” said Vladimir Lipunov, an astrophysicist at the Shternberg State Astronomy Institute.

“No one needs to be told what the Urals is,” Mr. Lipunov told the NTV television station. “A second hit in the same area is unlikely and everything could have been much, much worse.”

Siberia stretches the length of Asia, and there is a history of meteor and asteroid showers there. In 1908 a powerful explosion was reported near the Tunguska River in central Siberia, its impact so great that trees were flattened for 25 miles around. Generations of scientists have studied that event, analyzing particles that were driven into the Earth’s surface as far away as the South Pole. A study published in the 1980s concluded the object weighed a million tons.

In the United States, NASA alluded to the Tunguska incident when it said that it was watching closely an asteroid 150 feet in diameter expected to whiz past Earth on Friday at a distance of around 17,200 miles, the closest for many decades.

In a statement on its Web site, NASA said on Friday that there was no risk that the asteroid, 2012 DA14, would collide with Earth. But it would pass within “the belt of satellites in geostationary orbit, which is 22,200 miles above Earth’s surface.”

The asteroid is set to pass Earth at around 2:25 p.m. Eastern time, NASA said. “At the time of closest approach, the asteroid will be over the eastern Indian Ocean, off Sumatra,” the agency said.

“Asteroid 2012 DA14 will not impact Earth, but if another asteroid of a size similar to that of 2012 DA14 were to impact Earth, it would release approximately 2.5 megatons of energy in the atmosphere and would be expected to cause regional devastation,” NASA said. The asteroid will not be visible to the naked eye, the agency added.

Referring to the “Tunguska Event,” NASA said the impact of an asteroid just smaller than 2012 DA14 “is believed to have flattened about 825 square miles of forest in and around the Podkamennaya Tunguska River in what is now Krasnoyarsk Krai, Russia.”

Viktor Klimenko contributed reporting from Moscow, and Alan Cowell from London.

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Oscar Pistorius Weeps in Court as Prosecutors Seek Murder Charges

By Andrea Billups

02/15/2013 at 08:15 AM EST

Oscar Pistorius

Antonie de Ras/Reuters/Landov

Oscar Pistorius, the South African track star known as the Blade Runner, put his head in his hands and wept Friday as prosecutors said they would seek a charge of premeditated murder in the shooting of his girlfriend, model Reeva Steenkamp, the New York Times reports.

Pistorius, 26, appearing in a Pretoria courtroom, is accused of shooting Steenkamp, 30, whose body was found in a pool of blood in his gated home in Pretoria on Thursday. She was reportedly shot four times. He did not enter a plea on the murder charges and police said they would oppose any application for bail.

Pistorius rose to fame and became a national hero as a world-class sprinter while running in the London Olympics on carbon fiber blades. He was born without fibula bones and had amputations below the knees when he was an infant. He was the first Paralymic champion to run with able-bodied athletes in an Olympic games, making his debut last summer in London.

The murder charge has shocked South Africans who held the athlete up as a national hero. A grim Pistorious sat with his jaw clenched in the courtroom. At one point, his father Henke reached out to him, but Pistorius just walked on, teary-eyed.

Steenkamp had posted Valentine's Day messages of love on her Twitter account just hours before her death. "It should be a day of love for everyone," she Tweeted. Her family said they had no clue of trouble between the couple before her death.

Reeva Steenkamp and Oscar Pistorius

Gallo Images / REX USA

Police told reporters said they were interviewing witnesses, including neighbors. A 9 mm handgun was removed from the home by police.

Initial news accounts suggest that Pistorius, a gun enthusiast, had reportedly mistaken Steenkamp for an intruder. But police countered that story by disclosing previous police complaints of domestic problems at his home.

The court case will resume on Tuesday. Pistorius competed in the 2012 Olympics, running in the 400-meter race, where he reached the semi-finals. He also competed as a part of his country's 4x400 meter relay team. He has previously won two gold medals and a silver at the Paralympic Games, also held in London.

• With reporting by MIKE BEHR

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Study: Fish in drug-tainted water suffer reaction

BOSTON (AP) — What happens to fish that swim in waters tainted by traces of drugs that people take? When it's an anti-anxiety drug, they become hyper, anti-social and aggressive, a study found. They even get the munchies.

It may sound funny, but it could threaten the fish population and upset the delicate dynamics of the marine environment, scientists say.

The findings, published online Thursday in the journal Science, add to the mounting evidence that minuscule amounts of medicines in rivers and streams can alter the biology and behavior of fish and other marine animals.

"I think people are starting to understand that pharmaceuticals are environmental contaminants," said Dana Kolpin, a researcher for the U.S. Geological Survey who is familiar with the study.

Calling their results alarming, the Swedish researchers who did the study suspect the little drugged fish could become easier targets for bigger fish because they are more likely to venture alone into unfamiliar places.

"We know that in a predator-prey relation, increased boldness and activity combined with decreased sociality ... means you're going to be somebody's lunch quite soon," said Gregory Moller, a toxicologist at the University of Idaho and Washington State University. "It removes the natural balance."

Researchers around the world have been taking a close look at the effects of pharmaceuticals in extremely low concentrations, measured in parts per billion. Such drugs have turned up in waterways in Europe, the U.S. and elsewhere over the past decade.

They come mostly from humans and farm animals; the drugs pass through their bodies in unmetabolized form. These drug traces are then piped to water treatment plants, which are not designed to remove them from the cleaned water that flows back into streams and rivers.

The Associated Press first reported in 2008 that the drinking water of at least 51 million Americans carries low concentrations of many common drugs. The findings were based on questionnaires sent to water utilities, which reported the presence of antibiotics, sedatives, sex hormones and other drugs.

The news reports led to congressional hearings and legislation, more water testing and more public disclosure. To this day, though, there are no mandatory U.S. limits on pharmaceuticals in waterways.

The research team at Sweden's Umea University used minute concentrations of 2 parts per billion of the anti-anxiety drug oxazepam, similar to concentrations found in real waters. The drug belongs to a widely used class of medicines known as benzodiazepines that includes Valium and Librium.

The team put young wild European perch into an aquarium, exposed them to these highly diluted drugs and then carefully measured feeding, schooling, movement and hiding behavior. They found that drug-exposed fish moved more, fed more aggressively, hid less and tended to school less than unexposed fish. On average, the drugged fish were more than twice as active as the others, researcher Micael Jonsson said. The effects were more pronounced at higher drug concentrations.

"Our first thought is, this is like a person diagnosed with ADHD," said Jonsson, referring to attention deficit-hyperactivity disorder. "They become asocial and more active than they should be."

Tomas Brodin, another member of the research team, called the drug's environmental impact a global problem. "We find these concentrations or close to them all over the world, and it's quite possible or even probable that these behavioral effects are taking place as we speak," he said Thursday in Boston at the annual meeting of the American Association for the Advancement of Science.

Most previous research on trace drugs and marine life has focused on biological changes, such as male fish that take on female characteristics. However, a 2009 study found that tiny concentrations of antidepressants made fathead minnows more vulnerable to predators.

It is not clear exactly how long-term drug exposure, beyond the seven days in this study, would affect real fish in real rivers and streams. The Swedish researchers argue that the drug-induced changes could jeopardize populations of this sport and commercial fish, which lives in both fresh and brackish water.

Water toxins specialist Anne McElroy of Stony Brook University in New York agreed: "These lower chronic exposures that may alter things like animals' mating behavior or its ability to catch food or its ability to avoid being eaten — over time, that could really affect a population."

Another possibility, the researchers said, is that more aggressive feeding by the perch on zooplankton could reduce the numbers of these tiny creatures. Since zooplankton feed on algae, a drop in their numbers could allow algae to grow unchecked. That, in turn, could choke other marine life.

The Swedish team said it is highly unlikely people would be harmed by eating such drug-exposed fish. Jonsson said a person would have to eat 4 tons of perch to consume the equivalent of a single pill.

Researchers said more work is needed to develop better ways of removing drugs from water at treatment plants. They also said unused drugs should be brought to take-back programs where they exist, instead of being flushed down the toilet. And they called on pharmaceutical companies to work on "greener" drugs that degrade more easily.

Sandoz, one of three companies approved to sell oxazepam in the U.S., "shares society's desire to protect the environment and takes steps to minimize the environmental impact of its products over their life cycle," spokeswoman Julie Masow said in an emailed statement. She provided no details.

___

Online:

Overview of the drug: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682050.html

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San Diego ex-mayor used charity funds to cover gambling debts

SAN DIEGO — She married a fabulously wealthy man decades her elder, and became the first female mayor of San Diego. But when Maureen O'Connor left public life, she spent countless hours seated in front of video-poker machines.

Over a nine-year period, she wagered an estimated $1 billion, including millions from a charity set up by her late husband, who founded Jack in the Box.

That was the portrait that emerged in court Thursday as the frail former mayor tearfully acknowledged she skimmed more than $2 million from a charity founded by her late husband, Robert O. Peterson.

O'Connor, 66, admitted in a plea deal that she had a gambling addiction and is nearly destitute. Her lawyer, prominent defense attorney Eugene Iredale, suggested that a brain tumor may have impaired her reasoning; he gave reporters copies of her brain scan from a 2011 surgery.

O'Connor's rapidly declining medical condition "renders it highly improbable — if not impossible — that she could be brought to trial," according to court documents filed by federal prosecutors.

"This is a sad day for the city of San Diego," said Assistant U.S. Atty. Phillip Halpern. "Maureen O'Connor was born and raised in this town. She rose from humble origins.... She dedicated much of her life, personal and professional, to improving this city."

The $1-billion gambling binge stretched from 2000 to 2009, according to court documents. In 2008 and 2009, when the fortune she had inherited was not enough, she began taking from the R.P. Foundation to cover her losses.

Despite being ahead more than $1 billion at one point, O'Connor "suffered even larger gambling losses," according to prosecutors. Her net loss, Iredale said, was about $13 million.

She was considered such a high-roller that Las Vegas casinos would send a private jet to pick her up in San Diego. Records show that O'Connor won $100,000 at the Barona casino in San Diego County, while at roughly the same time she needed to cash a $100,000 check at the Bellagio in Las Vegas.

Those who knew the former political doyenne said she had become a recluse, inscrutable even to those she counted as friends.

"I considered myself one of her closest friends, but I would call her and she wouldn't return my call," said lawyer Louis Wolfsheimer. "I didn't want anything from her, just to know how she was. But it looked like she was becoming reclusive."

In a bargain with prosecutors, O'Connor agreed to repay $2,088,000 to the R.P. Foundation started by Peterson, which supported charities such as City of Hope, San Diego Hospice, and the Alzheimer's Assn., and was driven into insolvency in 2009 by O'Connor's misappropriation of funds, prosecutors said.

"I never meant to hurt the city," an emotional O'Connor told reporters gathered at a restaurant close to the federal courthouse. She promised to repay the foundation but declined to answer questions.

Prosecutors agreed to defer prosecution for two years. If O'Connor violates no further laws and makes restitution, the charge of making illegal financial transactions may be dismissed. Under the agreement, O'Connor acknowledged her guilt but was allowed to plead not guilty.

If convicted, O'Connor could have faced a maximum 10-year prison sentence and a fine of up to $250,000.

The daughter of a boxer who made his living as a cabbie and sometime bookie, O'Connor, a Democrat, rocketed to political prominence in 1971 when she was elected to the City Council at age 25. A onetime champion swimmer, O'Connor was working as a physical education teacher at a Catholic school and was pushed into politics when a group of students she took to a City Council meeting was treated rudely.

She met Peterson, 30 years her senior, when the Republican known for supporting liberal candidates and liberal causes offered to contribute to her council campaign. Political reform was in the air, and once elected, O'Connor helped persuade the council to adopt contribution limits, a reform later emulated by the state.

A close ally of then-Mayor Pete Wilson, O'Connor served two terms on the council and later was appointed to the Port Commission.

After marrying Peterson, O'Connor became a political anomaly in San Diego: although wealthy, she cultivated a base of political support in lower-income neighborhoods south of Interstate 8, the traditional dividing line of San Diego politics. When she traveled in minority neighborhoods, adults would come from their homes to wave at her; to all, she was known merely as Maureen.

As mayor, O'Connor organized a Russian arts festival and prowled the streets with the police chief, talking to prostitutes as she and Chief Bob Burgreen looked for information about a string of killings targeting streetwalkers. She went incognito as a homeless person to see how the homeless were treated in San Diego; she worked on a city garbage truck to experience the day-to-day life of blue-collar city workers.

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